From Computer Tyme Support Wiki

Revision as of 04:37, 29 May 2017

This is a discussion between Marc Perkel and Corey Zandowsky of Varian who makes the Varian ration equipment used by Kaiser. Corry is the guy who designs the equipment.

https://www.varian.com/about-varian/leadership-and-governance/executives/corey-zankowski-phd

My Initial Email

Hello Dr. Zankowski,

This is somewhat of an unusual request coming from a cancer patient, but I'm very high tech and hope to get your interest.

I am a patient at Kaiser and I have stage 4 NSCLC lung cancer. I talked my oncologist into trying something experimental as I am facing certain death otherwise. Have you heard of the "abscopal effect"? If not you can Google it but the idea is to use immune system stimulators with radiation to cause the immune system to recognize cancer as a target and go after it.

The abscopal effect has been noted a lot retrospectively where a patient is getting immunotherapy and then gets palliative radiation to stop a tumor from bleeding and a few month later the patient is cancer free. My goal is to try to trigger this effect. Kaiser is using your product and that's why I'm contacting you.

As I said, I'm high tech. I'm not a doctor but I learn really fast. My theory on what is likely to trigger the abscopal effect is not to try to kill the tumor but damage it in a very specific way. What I'm looking for is a pattern of radiation damage that puts necrotic dead cancer and dying cancer in contact with healthy tumor tissue so as to allow good interaction between the white blood cells and damaged and dead cancer tissue. I'm thinking that the damage should be towards the center of the tumor so that the collateral radiation damage will still be mostly within the tumor.

I have asked Kaiser for this and they say they understand what I want and can do it. I am contacting you however because I think the geometry of the radiation is very important and this technique has a good chance of working. I am wondering if you and your engineers want to get directly involved in planning a radiation geometry specifically to trigger the abscopal effect? If this works it will be very popular.

Marc Perkel Random Genius Gilroy CA.